Located 10 minutes' stroll from San Tommaso di Canterbury Cathedral, Casa Sarina Hotel Marsala offers Wi-Fi throughout the property and a free private car park. This guest house is located next door to Castello di Marsala and features bike loans and horse riding tours.

The accommodation is about 20 km from Vincenzo Florio airport and nearly a 5-minute drive from such cultural venues as Museo degli Arazzi Epoca Fiamminga. Historical sights here include Monumento ai Mille, which stands a few minutes' drive from the Casa Sarina Marsala. There is Cantine Florio 2 km away, while Stazione Autobus bus station within 600 metres of the property.

Casa Sarina Hotel offers rooms with a patio and a balcony featuring a trouser press and air conditioner, along with high-speed internet and a flat-screen TV with satellite channels. They are appointed with a work desk, and also feature tea/coffee making equipment. Bathrooms include a separate toilet, a sink, and a shower, along with comforts such as hairdryers and bathrobes. Guests can enjoy views of the city from the hotel.

There is an in-house bar onsite. Within a short walking distance of the accommodation, Nuova Pasticceria Alagna serves Italian dishes.